ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation

Heat shock protein (Hsp)70 is a molecular chaperone that maintains protein homoeostasis during cellular stress through two opposing mechanisms: protein refolding and degradation. However, the mechanisms by which Hsp70 balances these opposing functions under stress conditions remain unknown. Here, we...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Seo, Ji Hae, Park, Ji-Hyeon, Lee, Eun Ji, Vo, Tam Thuy Lu, Choi, Hoon, Kim, Jun Yong, Jang, Jae Kyung, Wee, Hee-Jun, Lee, Hye Shin, Jang, Se Hwan, Park, Zee Yong, Jeong, Jaeho, Lee, Kong-Joo, Seok, Seung-Hyeon, Park, Jin Young, Lee, Bong Jin, Lee, Mi-Ni, Oh, Goo Taeg, Kim, Kyu-Won
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059642/
https://ncbi.nlm.nih.gov/pubmed/27708256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12882
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