A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.

Lignende værker

• Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor.
  af: Naldini, L, et al.
  Udgivet: (1992)
• Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor.
  af: Naldini, L, et al.
  Udgivet: (1991)
• Transfer of motogenic and invasive response to scatter factor/hepatocyte growth factor by transfection of human MET protooncogene.
  af: Giordano, S, et al.
  Udgivet: (1993)
• Functional map and domain structure of MET, the product of the c-met protooncogene and receptor for hepatocyte growth factor/scatter factor
  af: Gherardi, Ermanno, et al.
  Udgivet: (2003)
• Structural basis of hepatocyte growth factor/scatter factor and MET signalling
  af: Gherardi, Ermanno, et al.
  Udgivet: (2006)