A functional domain in the heavy chain of scatter factor/hepatocyte growth factor binds the c-Met receptor and induces cell dissociation but not mitogenesis.

We recently found that scatter factor (SF), a cell motility factor with a multimodular structure, is identical to hepatocyte growth factor (HGF), a potent mitogen of various cell types. SF/HGF is the ligand of the c-Met receptor tyrosine kinase. Here we used transient expression of naturally occurri...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Hartmann, G, Naldini, L, Weidner, K M, Sachs, M, Vigna, E, Comoglio, P M, Birchmeier, W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50595/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1280830/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11574
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