CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis

It has been shown that HPV16 E7, but not other genotypes, can bind to scaffold protein CUL2 during inducing cervical carcinogenesis, but the expression level, associated regulating mechanism, and potential carcinogenicity of CUL2 itself is still unknown as yet. Here, we demonstrated that CUL2 was sp...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Xu, Junfen, Fang, Yifeng, Wang, Xinyu, Wang, Fenfen, Tian, Qifang, Li, Ying, Xie, Xing, Cheng, Xiaodong, Lu, Weiguo
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058775/
https://ncbi.nlm.nih.gov/pubmed/27153550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9127
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