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CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis

It has been shown that HPV16 E7, but not other genotypes, can bind to scaffold protein CUL2 during inducing cervical carcinogenesis, but the expression level, associated regulating mechanism, and potential carcinogenicity of CUL2 itself is still unknown as yet. Here, we demonstrated that CUL2 was sp...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Xu, Junfen, Fang, Yifeng, Wang, Xinyu, Wang, Fenfen, Tian, Qifang, Li, Ying, Xie, Xing, Cheng, Xiaodong, Lu, Weiguo
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058775/
https://ncbi.nlm.nih.gov/pubmed/27153550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9127
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