Growth suppression by MYC inhibition in small cell lung cancer cells with TP53 and RB1 inactivation

Small cell lung cancer (SCLC) is the most aggressive type of lung cancer with high mortality. One of the MYC family genes, MYC, MYCL or MYCN, is amplified in ~20% of the SCLCs; therefore, MYC proteins are potential therapeutic targets in SCLC patients. We investigated the therapeutic impact of Omomy...

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Udgivet i:Oncotarget
Main Authors: Fiorentino, Francesco Paolo, Tokgün, Elvan, Solé-Sánchez, Sònia, Giampaolo, Sabrina, Tokgün, Onur, Jauset, Toni, Kohno, Takashi, Perucho, Manuel, Soucek, Laura, Yokota, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058735/
https://ncbi.nlm.nih.gov/pubmed/27105536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8826
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