KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment

Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for patients, after surgery and radiotherapy, consists of temozolomide (TMZ), a methylating agent that blocks tumor cell proliferation. Currently,...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: D'Alessandro, Giuseppina, Grimaldi, Alfonso, Chece, Giuseppina, Porzia, Alessandra, Esposito, Vincenzo, Santoro, Antonio, Salvati, Maurizio, Mainiero, Fabrizio, Ragozzino, Davide, Angelantonio, Silvia Di, Wulff, Heike, Catalano, Myriam, Limatola, Cristina
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058717/
https://ncbi.nlm.nih.gov/pubmed/27096953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8761
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