KCa3.1 channel inhibition sensitizes malignant gliomas to temozolomide treatment

Malignant gliomas are among the most frequent and aggressive cerebral tumors, characterized by high proliferative and invasive indexes. Standard therapy for patients, after surgery and radiotherapy, consists of temozolomide (TMZ), a methylating agent that blocks tumor cell proliferation. Currently,...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: D'Alessandro, Giuseppina, Grimaldi, Alfonso, Chece, Giuseppina, Porzia, Alessandra, Esposito, Vincenzo, Santoro, Antonio, Salvati, Maurizio, Mainiero, Fabrizio, Ragozzino, Davide, Angelantonio, Silvia Di, Wulff, Heike, Catalano, Myriam, Limatola, Cristina
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058717/
https://ncbi.nlm.nih.gov/pubmed/27096953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8761
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