KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages

Among the strategies adopted by glioma to successfully invade the brain parenchyma is turning the infiltrating microglia/macrophages (M/MΦ) into allies, by shifting them toward an anti-inflammatory, pro-tumor phenotype. Both glioma and infiltrating M/MΦ cells express the Ca(2+)-activated K(+) channe...

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Publicat a:Cell Death Dis
Autors principals: Grimaldi, A, D'Alessandro, G, Golia, M T, Grössinger, E M, Di Angelantonio, S, Ragozzino, D, Santoro, A, Esposito, V, Wulff, H, Catalano, M, Limatola, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855657/
https://ncbi.nlm.nih.gov/pubmed/27054329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.73
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