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Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma

Glioblastoma is the most frequent malignant brain tumor. Even with aggressive treatment, prognosis for patients is poor. One characteristic of glioblastoma cells is its intrinsic resistance to apoptosis. Therefore, drugs that induce alternative cell deaths could be interesting to evaluate as alterna...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Xipell, Enric, Gonzalez-Huarriz, Marisol, de Irujo, Juan Jose Martinez, García-Garzón, Antonia, Lang, Fred F., Jiang, Hong, Fueyo, Juan, Gomez-Manzano, Candelaria, Alonso, Marta M.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058706/
https://ncbi.nlm.nih.gov/pubmed/27121320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8905
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