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Crosstalk between insulin-like growth factor-1 and angiotensin-II in dopaminergic neurons and glial cells: role in neuroinflammation and aging

The local renin-angiotensin system (RAS) and insulin-like growth factor 1 (IGF-1) have been involved in longevity, neurodegeneration and aging-related dopaminergic degeneration. However, it is not known whether IGF-1 and angiotensin-II (AII) activate each other. In the present study, AII, via type 1...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Rodriguez-Perez, Ana I., Borrajo, Ana, Diaz-Ruiz, Carmen, Garrido-Gil, Pablo, Labandeira-Garcia, Jose L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058663/
https://ncbi.nlm.nih.gov/pubmed/27167199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9174
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