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Hinokitiol protects primary neuron cells against prion peptide-induced toxicity via autophagy flux regulated by hypoxia inducing factor-1

Prion diseases are fatal neurodegenerative disorders that are derived from structural changes of the native PrPc. Recent studies indicated that hinokitiol induced autophagy known to major function that keeps cells alive under stressful conditions. We investigated whether hinokitiol induces autophagy...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Moon, Ji-Hong, Lee, Ju-Hee, Lee, You-Jin, Park, Sang-Youel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058655/
https://ncbi.nlm.nih.gov/pubmed/27074563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8670
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