RhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vessels

BACKGROUND: Diabetes-induced vascular dysfunction may arise from reduced nitric oxide (NO) availability, following interaction with superoxide to form peroxynitrite. Peroxynitrite can induce formation of 3-nitrotyrosine-modified proteins. RhoA/ROCK signaling is also involved in diabetes-induced vasc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cardiovasc Disord
Main Authors: Sun, Zhijun, Wu, Xing, Li, Weiping, Peng, Hui, Shen, Xuhua, Ma, Lu, Liu, Huirong, Li, Hongwei
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057502/
https://ncbi.nlm.nih.gov/pubmed/27724862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12872-016-0372-6
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