Results and validation of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine.
Tacrine has been studied in two clinical trials of identical design in patients with probable Alzheimer disease. One trial enrolled patients in the United States, while the other enrolled patients in France. A population pharmacodynamic model has been used to describe the cognitive component of the...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1992
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50573/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11471 |
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