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Nuclear envelope rupture is induced by actin-based nucleus confinement

Repeated rounds of nuclear envelope (NE) rupture and repair have been observed in laminopathy and cancer cells and result in intermittent loss of nucleus compartmentalization. Currently, the causes of NE rupture are unclear. Here, we show that NE rupture in cancer cells relies on the assembly of con...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Hatch, Emily M., Hetzer, Martin W.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057282/
https://ncbi.nlm.nih.gov/pubmed/27697922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201603053
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