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Catastrophic nuclear envelope collapse in cancer cell micronuclei

During mitotic exit missegregated chromosomes can recruit their own nuclear envelope (NE) to form micronuclei (MN). MN have reduced functioning compared to primary nuclei in the same cell, although the two compartments appear to be structurally comparable. Here we show that over 60% of MN undergo an...

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Detalhes bibliográficos
Main Authors: Hatch, Emily M., Fischer, Andrew H., Deerinck, Thomas J., Hetzer, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749778/
https://ncbi.nlm.nih.gov/pubmed/23827674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.007
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