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Catastrophic nuclear envelope collapse in cancer cell micronuclei

During mitotic exit missegregated chromosomes can recruit their own nuclear envelope (NE) to form micronuclei (MN). MN have reduced functioning compared to primary nuclei in the same cell, although the two compartments appear to be structurally comparable. Here we show that over 60% of MN undergo an...

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Autores principales: Hatch, Emily M., Fischer, Andrew H., Deerinck, Thomas J., Hetzer, Martin W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749778/
https://ncbi.nlm.nih.gov/pubmed/23827674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.007
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