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Catastrophic nuclear envelope collapse in cancer cell micronuclei

During mitotic exit missegregated chromosomes can recruit their own nuclear envelope (NE) to form micronuclei (MN). MN have reduced functioning compared to primary nuclei in the same cell, although the two compartments appear to be structurally comparable. Here we show that over 60% of MN undergo an...

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Autors principals: Hatch, Emily M., Fischer, Andrew H., Deerinck, Thomas J., Hetzer, Martin W.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749778/
https://ncbi.nlm.nih.gov/pubmed/23827674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.06.007
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