A Naturally Occurring Antibody Fragment Neutralizes Infectivity of Diverse Infectious Agents

A phosphorylated peptide, named K40H, derived from the constant region of IgMs was detected in human serum by liquid chromatography coupled to high-resolution mass spectrometry. Synthetic K40H proved to exert a potent in vitro activity against fungal pathogens, and to inhibit HIV-1 replication in vi...

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發表在:Sci Rep
Main Authors: Polonelli, Luciano, Ciociola, Tecla, Elviri, Lisa, Zanello, Pier Paolo, Giovati, Laura, Arruda, Denise C., Muñoz, Julián E., Mortara, Renato A., Morace, Giulia, Borghi, Elisa, Galati, Serena, Marin, Oriano, Casoli, Claudio, Pilotti, Elisabetta, Ronzi, Paola, Travassos, Luiz R., Magliani, Walter, Conti, Stefania
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5057116/
https://ncbi.nlm.nih.gov/pubmed/27725769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35018
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