Intrinsic Resistance to 5-Fluorouracil in a Brain Metastatic Variant of Human Breast Cancer Cell Line, MDA-MB-231BR

Although drug resistance is often observed in metastatic recurrence of breast cancer, little is known about the intrinsic drug resistance in such metastases. In the present study, we found, for the first time, that MDA-MB-231BR, a brain metastatic variant of a human breast cancer cell line, was refr...

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Publicat a:PLoS One
Autors principals: Sagara, Atsunobu, Igarashi, Katsuhide, Otsuka, Maky, Karasawa, Takeshi, Gotoh, Noriko, Narita, Michiko, Kuzumaki, Naoko, Narita, Minoru, Kato, Yoshinori
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056764/
https://ncbi.nlm.nih.gov/pubmed/27723829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164250
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