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Dual Roles of IFN-γ and IL-4 in the Natural History of Murine Autoimmune Cholangitis: IL-30 and Implications for Precision Medicine

Primary biliary cirrhosis (PBC) is a progressive autoimmune liver disease with a long natural history. The pathogenesis of PBC is thought to be orchestrated by Th1 and/or Th17. In this study, we investigated the role of CD4(+) helper T subsets and their cytokines on PBC using our previous establishe...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Syu, Bi-Jhen, Loh, Chia-En, Hsueh, Yu-Hsin, Gershwin, M. Eric, Chuang, Ya-Hui
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056512/
https://ncbi.nlm.nih.gov/pubmed/27721424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34884
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