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Modulation of the E. coli rpoH Temperature Sensor Using Triptycene-Based Small Molecules

Regulation of the heat shock response (HSR) is essential in all living systems. In E. coli, the HSR is regulated by the alternative σ factor, σ(32), which is encoded by the rpoH gene. The mRNA of rpoH adopts a complex secondary structure critical for proper translation of the σ(32) protein. At low t...

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Bibliografiske detaljer
Udgivet i:Angew Chem Int Ed Engl
Main Authors: Barros, Stephanie A., Yoon, Ina, Chenoweth, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056428/
https://ncbi.nlm.nih.gov/pubmed/27240201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201601626
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