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Triptycene-based small molecules modulate (CAG)·(CTG) repeat junctions

Nucleic acid three-way junctions (3WJs) play key roles in biological processes such as nucleic acid replication in addition to being implicated as dynamic transient intermediates in trinucleotide repeat sequences. Structural modulation of specific nucleic acid junctions could allow for control of bi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Barros, Stephanie A., Chenoweth, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538686/
https://ncbi.nlm.nih.gov/pubmed/26366282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc01595b
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