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Spermine and spermidine protection of plasmid DNA against single-strand breaks induced by singlet oxygen.

Oxidative damage to DNA induced by singlet molecular oxygen (1O2*) includes single-strand breaks, which the biologically occurring 1O2* quenchers spermine and spermidine are shown to prevent. These polyamines at a physiological concentration (10 mM) reduce the percentage of the open circular form of...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Khan, A U, Di Mascio, P, Medeiros, M H, Wilson, T
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1992
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC50564/
https://ncbi.nlm.nih.gov/pubmed/1454831
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