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Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide
In the innate immune system, pattern recognition receptors (PRRs) specifically recognize ligands derived from bacteria or viruses, to trigger the responsible downstream pathways. DEAD box protein 41 (DDX41) is an intracellular PRR that triggers the downstream pathway involving the adapter STING, the...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5056382/ https://ncbi.nlm.nih.gov/pubmed/27721487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34756 |
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