Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide

In the innate immune system, pattern recognition receptors (PRRs) specifically recognize ligands derived from bacteria or viruses, to trigger the responsible downstream pathways. DEAD box protein 41 (DDX41) is an intracellular PRR that triggers the downstream pathway involving the adapter STING, the...

Full description

Saved in:
Bibliographic Details
Published in:Sci Rep
Main Authors: Omura, Hiroki, Oikawa, Daisuke, Nakane, Takanori, Kato, Megumi, Ishii, Ryohei, Ishitani, Ryuichiro, Tokunaga, Fuminori, Nureki, Osamu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056382/
https://ncbi.nlm.nih.gov/pubmed/27721487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34756
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items