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Oncogenic fingerprint of epidermal growth factor receptor pathway and emerging epidermal growth factor receptor blockade resistance in colorectal cancer

Epidermal growth factor receptor (EGFR) has been an attractive target for treatment of epithelial cancers, including colorectal cancer (CRC). Evidence from clinical trials indicates that cetuximab and panitumumab (anti-EGFR monoclonal antibodies) have clinical activity in patients with metastatic CR...

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Dettagli Bibliografici
Pubblicato in:World J Clin Oncol
Autori principali: Sobani, Zain A, Sawant, Ashwin, Jafri, Mikram, Correa, Amit Keith, Sahin, Ibrahim Halil
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056326/
https://ncbi.nlm.nih.gov/pubmed/27777877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5306/wjco.v7.i5.340
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