Curcumin Represses NLRP3 Inflammasome Activation via TLR4/MyD88/NF-κB and P2X7R Signaling in PMA-Induced Macrophages

Aims: In the NOD-like receptor (NLR) family, the pyrin domain containing 3 (NLRP3) inflammasome is closely related to the progression of atherosclerosis. This study aimed to assess the effects of curcumin on NLRP3 inflammasome in phorbol 12-myristate 13-acetate (PMA)-induced macrophages and explore...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Kong, Fanqi, Ye, Bozhi, Cao, Jiatian, Cai, Xueli, Lin, Lu, Huang, Shanjun, Huang, Weijian, Huang, Zhouqing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056188/
https://ncbi.nlm.nih.gov/pubmed/27777559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00369
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