Oriented collagen fibers direct tumor cell intravasation

In this work, we constructed a Collagen I–Matrigel composite extracellular matrix (ECM). The composite ECM was used to determine the influence of the local collagen fiber orientation on the collective intravasation ability of tumor cells. We found that the local fiber alignment enhanced cell–ECM int...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Han, Weijing, Chen, Shaohua, Yuan, Wei, Fan, Qihui, Tian, Jianxiang, Wang, Xiaochen, Chen, Longqing, Zhang, Xixiang, Wei, Weili, Liu, Ruchuan, Qu, Junle, Jiao, Yang, Austin, Robert H., Liu, Liyu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5056065/
https://ncbi.nlm.nih.gov/pubmed/27663743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610347113
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