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Cyclopamine-loaded Core-crosslinked Polymeric Micelles Enhance Radiation Response in Pancreatic Cancer and Pancreatic Stellate Cells

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers. Cyclopamine (CPA), a potent inhibitor for sonic hedgehog pathway (SHH), shows great promises in PDAC treatment, including the disruption of tumor-associated stroma, and enhancement of radiation therapy. However, CPA is insolu...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Pharm
Asıl Yazarlar: Zhao, Jun, Wu, Chunhui, Abbruzzese, James, Hwang, Rosa F., Li, Chun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055750/
https://ncbi.nlm.nih.gov/pubmed/25936695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp500875f
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