Severe active C3 glomerulonephritis triggered by immune complexes and inactivated after eculizumab therapy

BACKGROUND: Understanding the role of alternative complement pathway dysregulation in membranoproliferative glomerulonephritis (MPGN) has led to a dramatic shift in its classification into two subgroups: immune complex-mediated MPGN and complement-mediated MPGN, consisting of dense deposit disease a...

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Bibliographic Details
Published in:Diagn Pathol
Main Authors: Kersnik Levart, Tanja, Ferluga, Dušan, Vizjak, Alenka, Mraz, Jerica, Kojc, Nika
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Case Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055692/
https://ncbi.nlm.nih.gov/pubmed/27717365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0547-6
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