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SPECT Imaging of Inflammatory Response in Ischemic–Reperfused Rat Hearts Using a (99m)Tc-Labeled Dual-Domain Cytokine Ligand

Soluble tumor necrosis factor (TNF) receptor-2 (TNFR2) and interleukin-1 receptor antagonist (IL-1ra) were fused to the Fc portion of IgG1 using recombinant DNA technology. The resulting dual-domain cytokine ligand, TNFR2-Fc-IL-1ra, specifically binds to TNF and to the type I IL-1 receptor (IL-1RI)....

詳細記述

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書誌詳細
出版年:J Nucl Med
主要な著者: Liu, Zhonglin, Barber, Christy, Wan, Li, Liu, Shan, Hui, Mizhou M., Furenlid, Lars R., Xu, Hua, Woolfenden, James M.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055402/
https://ncbi.nlm.nih.gov/pubmed/24179185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.113.123497
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