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Characterization of (99m)Tc-labeled cytokine ligands for inflammation imaging via TNF and IL-1 pathways
INTRODUCTION: TNFR2-Fc and IL-1ra-Fc are recombinant cytokine ligands that target TNF and IL-1. TNFR2-Fc-IL-1ra, a dual-domain agent that incorporates both ligands, allows bifunctional binding of IL-1 receptors and TNF. This study was designed to characterize (99m)Tc-labeled forms of these ligands,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3443298/ https://ncbi.nlm.nih.gov/pubmed/22749187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2012.05.003 |
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