Vimentin intermediate filaments template microtubule networks to enhance persistence in cell polarity and directed migration

Increased expression of vimentin intermediate filaments (VIF) enhances directed cell migration, but the mechanism behind VIF’s effect on motility is not understood. VIF interact with microtubules, whose organization contributes to polarity maintenance in migrating cells. Here we characterize the dyn...

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Publicat a:Cell Syst
Autors principals: Gan, Zhuo, Ding, Liya, Burckhardt, Christoph J., Lowery, Jason, Zaritsky, Assaf, Sitterley, Karlyndsay, Mota, Andressa, Costigliola, Nancy, Starker, Colby G., Voytas, Daniel F., Tytell, Jessica, Goldman, Robert D., Danuser, Gaudenz
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055390/
https://ncbi.nlm.nih.gov/pubmed/27667364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.08.007
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