Vimentin intermediate filaments template microtubule networks to enhance persistence in cell polarity and directed migration

Increased expression of vimentin intermediate filaments (VIF) enhances directed cell migration, but the mechanism behind VIF’s effect on motility is not understood. VIF interact with microtubules, whose organization contributes to polarity maintenance in migrating cells. Here we characterize the dyn...

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Publicado en:Cell Syst
Autores principales: Gan, Zhuo, Ding, Liya, Burckhardt, Christoph J., Lowery, Jason, Zaritsky, Assaf, Sitterley, Karlyndsay, Mota, Andressa, Costigliola, Nancy, Starker, Colby G., Voytas, Daniel F., Tytell, Jessica, Goldman, Robert D., Danuser, Gaudenz
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055390/
https://ncbi.nlm.nih.gov/pubmed/27667364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.08.007
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