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Gdown1 Associates Efficiently with RNA Polymerase II after Promoter Clearance and Displaces TFIIF during Transcript Elongation

Pausing during the earliest stage of transcript elongation by RNA polymerase II (Pol II) is a nearly universal control point in metazoan gene expression. The substoichiometric Pol II subunit Gdown1 facilitates promoter proximal pausing in vitro in extract-based transcription reactions, out-competes...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: DeLaney, Elizabeth, Luse, Donal S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055313/
https://ncbi.nlm.nih.gov/pubmed/27716820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163649
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