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Transcription factor TFIIF is not required for initiation by RNA polymerase II, but it is essential to stabilize transcription factor TFIIB in early elongation complexes

Transcription factors TFIIB and TFIIF are both required for RNA polymerase II preinitiation complex (PIC) assembly, but their roles at and downstream of initiation are not clear. We now show that TFIIF phosphorylated by casein kinase 2 remains competent to support PIC assembly but is not stably reta...

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Bibliografiska uppgifter
Huvudupphovsmän: Čabart, Pavel, Újvári, Andrea, Pal, Mahadeb, Luse, Donal S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179120/
https://ncbi.nlm.nih.gov/pubmed/21896726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104591108
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