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Targeted TET oxidase activity through methyl‐CpG‐binding domain extensively suppresses cancer cell proliferation
DNA methyltransferase (DNMT) inhibitors are epigenetic drugs used to treat myelodysplastic syndrome. They not only induce DNA demethylation but also have significant cytostatic and cytotoxic effects; however, the relationships between these characteristics have not been established yet due to the la...
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Publicado no: | Cancer Med |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5055179/ https://ncbi.nlm.nih.gov/pubmed/27457352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.830 |
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