Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells

Understanding human embryonic ventral midbrain is of major interest for Parkinson’s disease. However, the cell types, their gene expression dynamics, and their relationship to commonly used rodent models remain to be defined. We performed single-cell RNA sequencing to examine ventral midbrain develo...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: La Manno, Gioele, Gyllborg, Daniel, Codeluppi, Simone, Nishimura, Kaneyasu, Salto, Carmen, Zeisel, Amit, Borm, Lars E., Stott, Simon R.W., Toledo, Enrique M., Villaescusa, J. Carlos, Lönnerberg, Peter, Ryge, Jesper, Barker, Roger A., Arenas, Ernest, Linnarsson, Sten
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055122/
https://ncbi.nlm.nih.gov/pubmed/27716510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.027
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