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Homology modeling, molecular dynamics, and virtual screening of NorA efflux pump inhibitors of Staphylococcus aureus

Emerging drug resistance in clinical isolates of Staphylococcus aureus might be implicated to the overexpression of NorA efflux pump which is capable of extruding numerous structurally diverse compounds. However, NorA efflux pump is considered as a potential drug target for the development of efflux...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Bhaskar, Baki Vijaya, Babu, Tirumalasetty Muni Chandra, Reddy, Netala Vasudeva, Rajendra, Wudayagiri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055111/
https://ncbi.nlm.nih.gov/pubmed/27757014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S113556
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