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Substrates with engineered step changes in rigidity induce traction force polarity and durotaxis

Rigidity sensing plays a fundamental role in multiple cell functions ranging from migration, to proliferation and differentiation(1–5). During migration, single cells have been reported to preferentially move toward more rigid regions of a substrate in a process termed durotaxis. Durotaxis could con...

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Vydáno v:Cell Mol Bioeng
Hlavní autoři: Breckenridge, Mark T., Desai, Ravi A., Yang, Michael T., Fu, Jianping, Chen, Christopher S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055071/
https://ncbi.nlm.nih.gov/pubmed/27721906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12195-013-0307-6
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