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Effect of nordihydroguaiaretic acid on cell viability and glucose transport in human leukemic cell lines

The polyphenol nordihydroguaiaretic acid (NDGA) has antineoplastic properties, hence it is critical to understand its action at the molecular level. Here, we establish that NDGA inhibits glucose uptake and cell viability in leukemic HL‐60 and U‐937 cell lines. We monitored hexose uptake using radio‐...

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Detalhes bibliográficos
Publicado no:FEBS Open Bio
Main Authors: Leon, David, Parada, Daniela, Vargas‐Uribe, Mauricio, Perez, Alejandra A., Ojeda, Lorena, Zambrano, Angara, Reyes, Alejandro M., Salas, Mónica
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5055036/
https://ncbi.nlm.nih.gov/pubmed/27761359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12106
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