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Interfering with leukemic stem cells

Kinase inhibitors such as imatinib (Gleevec) have improved the outlook for many patients with chronic myeloid leukemia and related blood disorders. But such drugs fail to target the leukemia stem cell population and may not be curative. Krause and Van Etten discuss several clinical studies that sugg...

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Bibliographic Details
Main Authors: Krause, Daniela S., Van Etten, Richard A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3490184/
https://ncbi.nlm.nih.gov/pubmed/18463658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm0508-494
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