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Comparing the discriminative stimulus effects of modulators of GABA(A) receptors containing α(4)-δ subunits with those of gaboxadol in rats

RATIONALE: Gaboxadol is a selective agonist at GABA(A) receptors that contain α(4)-δ subunits, and it produces anxiolytic and sedative effects. Although adverse effects preclude its clinical use, its mechanism of action suggests that those receptors might provide novel therapeutic targets, particula...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Zanettini, Claudio, Pressly, Jeffrey D., Ibarra, Miguel H., Smith, Kelsey R., Gerak, Lisa R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054722/
https://ncbi.nlm.nih.gov/pubmed/26900079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-016-4243-8
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