Gabapentin increases expression of δ subunit-containing GABA(A) receptors

BACKGROUND: Gabapentin is a structural analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA). Its anticonvulsant, analgesic and anxiolytic properties suggest that it increases GABAergic inhibition; however, the molecular basis for these effects is unknown as gabapentin does not direct...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Yu, Jieying, Wang, Dian-Shi, Bonin, Robert P., Penna, Antonello, Alavian-Ghavanini, Ali, Zurek, Agnieszka A., Rauw, Gail, Baker, Glen B., Orser, Beverley A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491385/
https://ncbi.nlm.nih.gov/pubmed/30878595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.008
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