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How strong is the evidence that Parkinson’s disease is a prion disorder?

PURPOSE OF REVIEW: We describe evidence supporting the hypothesis that α-synuclein has a prion-like role in Parkinson’s disease and related α-synucleinopathies, and discuss how this novel thinking impacts the development of diagnostics and disease-modifying therapies. RECENT FINDINGS: Observations t...

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Detalhes bibliográficos
Publicado no:Curr Opin Neurol
Main Authors: Brundin, Patrik, Ma, Jiyan, Kordower, Jeffrey H
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054685/
https://ncbi.nlm.nih.gov/pubmed/27257944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WCO.0000000000000349
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