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PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness
PAK1 confers resistance to the estrogen antagonist tamoxifen in breast cancer. However, a role for PAK1 remains to be elucidated for chemoresistance and prognosis in non-small cell lung cancer (NSCLC). We provide evidence that PAK1 confers cisplatin resistance by increasing β-catenin expression thro...
Guardat en:
| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5054675/ https://ncbi.nlm.nih.gov/pubmed/27713506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34933 |
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