Human fusion proteins between interleukin 2 and IgM heavy chain are cytotoxic for cells expressing the interleukin 2 receptor.

We have constructed a hybrid cDNA coding for a fusion protein between human interleukin 2 and a truncated heavy chain from human immunoglobulin M. The protein encoded by this cDNA contains the entire interleukin 2 sequence including its signal peptide, fused at its C terminus to domains 2 to 4 of th...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Vié, H, Gauthier, T, Breathnach, R, Bonneville, M, Godard, A, Dietrich, J, Karam, G, Gesnel, M C, Peyrat, M A, Jacques, Y
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50545/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454817/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11337
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