Targeting Epstein-Barr virus–transformed B lymphoblastoid cells using antibodies with T-cell receptor–like specificities

Epstein-Barr virus (EBV) is an oncovirus associated with several human malignancies including posttransplant lymphoproliferative disease in immunosuppressed patients. We show here that anti-EBV T-cell receptor–like monoclonal antibodies (TCR-like mAbs) E1, L1, and L2 bound to their respective HLA-A*...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: Lai, Junyun, Tan, Wei Jian, Too, Chien Tei, Choo, Joanna Ai Ling, Wong, Lan Hiong, Mustafa, Fatimah Bte, Srinivasan, Nalini, Lim, Angeline Pei Chiew, Zhong, Youjia, Gascoigne, Nicholas R. J., Hanson, Brendon J., Chan, Soh Ha, Chen, Jianzhu, MacAry, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5054486/
https://ncbi.nlm.nih.gov/pubmed/27338099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-707836
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