MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation

The female genital tract (FGT) mucosa is a critically important site for immune defense against microbes. Mucosal-associated invariant T (MAIT) cells are an innate-like T cell population that recognizes microbial riboflavin metabolite antigens in an MR1-dependent manner. The role of MAIT cells in th...

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Gepubliceerd in:Mucosal Immunol
Hoofdauteurs: Gibbs, Anna, Leeansyah, Edwin, Introini, Andrea, Paquin-Proulx, Dominic, Hasselrot, Klara, Andersson, Emilia, Broliden, Kristina, Sandberg, Johan K., Tjernlund, Annelie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053908/
https://ncbi.nlm.nih.gov/pubmed/27049062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.30
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