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Transcriptome–metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals network level interactions in toxicologic mechanism

A combination of the herbicide paraquat (PQ) and fungicide maneb (MB) has been linked to Parkinson's disease. Previous studies show that this involves an additive toxicity with at least two different mechanisms. However, detailed understanding of mixtures is often difficult to elucidate because...

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Bibliografski detalji
Izdano u:Toxicol Rep
Glavni autori: Roede, James R., Uppal, Karan, Park, Youngja, Tran, ViLinh, Jones, Dean P.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053767/
https://ncbi.nlm.nih.gov/pubmed/27722094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.07.006
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