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Transcriptome–metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals network level interactions in toxicologic mechanism

A combination of the herbicide paraquat (PQ) and fungicide maneb (MB) has been linked to Parkinson's disease. Previous studies show that this involves an additive toxicity with at least two different mechanisms. However, detailed understanding of mixtures is often difficult to elucidate because...

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Detalhes bibliográficos
Publicado no:Toxicol Rep
Main Authors: Roede, James R., Uppal, Karan, Park, Youngja, Tran, ViLinh, Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053767/
https://ncbi.nlm.nih.gov/pubmed/27722094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxrep.2014.07.006
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