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PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

PICH is an SNF2-family DNA translocase that appears to play a role specifically in mitosis. Characterization of PICH in human cells led to the initial discovery of “ultra-fine DNA bridges” (UFBs) that connect the 2 segregating DNA masses in the anaphase of mitosis. These bridge structures, which ari...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Nielsen, Christian F., Hickson, Ian D.
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053587/
https://ncbi.nlm.nih.gov/pubmed/27565185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1222336
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