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XRN1 Is a Species-Specific Virus Restriction Factor in Yeasts
In eukaryotes, the degradation of cellular mRNAs is accomplished by Xrn1 and the cytoplasmic exosome. Because viral RNAs often lack canonical caps or poly-A tails, they can also be vulnerable to degradation by these host exonucleases. Yeast lack sophisticated mechanisms of innate and adaptive immuni...
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| Publicado en: | PLoS Pathog |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053509/ https://ncbi.nlm.nih.gov/pubmed/27711183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005890 |
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